The Angel Arch branch leaves Upper Salt Creek. From the Needles Campground trailhead, the route follows Peekaboo into the canyon; Cathedral Butte is the southern trailhead, and a through-hike needs a vehicle shuttle. Mileage varies by starting point and route, so use a topographic map to plan camps and daylight rather than relying on one advertised total.
Salt Creek is not an easy trail corridor: deep sand, reeds and dense vegetation can slow you down or hide the path, and seasonal flooding can change the route. Mosquitoes and gnats can be common from early summer into autumn. Most backpackers spend two or three nights in the canyon, and a full through-hike in two days or less is discouraged. Roads to either end can be impassable or require high-clearance four-wheel drive. For Peekaboo, park at Cave Springs/Salt Creek Gate and walk the road instead of parking along Salt Creek or Horse Canyon, where flash flooding is a risk.